Dr Dan Hart

The Royal London Hospital, Barts Health NHS Trust, London, UK,
North London Adult and Paediatric Haemophilia Networks.
Barts and The London School of Medicine and Dentistry, Queen Mary University London.
Dan Hart is a Senior Lecturer in Haemostasis and Honorary Consultant Haematologist. He has a PhD in cellular immunology and completed his haemophilia specialization at The Royal Free Hospital and Great Ormond Street Hospital for Children haemophilia centres. He specializes in inherited bleeding disorders and has an evolving research programme exploring the immunological complications of haemophilia treatment. Current projects include: assay development for antibody detection and epitope identification; computational modeling of fVIII peptide presentation by MHC class II to CD4 T cells; transcriptome analysis monitoring gene expression dynamics after first exposure to fVIII concentrate. He is a collaborator with the European INSIGHT group investigating inhibitor formation in a large cohort of mild/moderate haemophilia A and also with University of Hertfordshire health psychology team investigating prophylaxis adherence in adolescents and young adults. He is secretary to the UK Haemophilia Centre Doctors Organisation Inhibitor Working party, contributing to guideline publication and analysis of national data.
Dr Hart leads the Royal London WFH twinning programme with two large state hospitals in Dhaka, Bangladesh, facilitating their move to cryoprecipitate use from whole blood / FFP and recently organizing laboratory and nursing workshops.